STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4(+) T cells

Signal transducer and activator of transcription 3 (STAT3) integrates key signals of cell surface immune receptors, yet its precise role in cluster of differentiation (CD)4(+) T cells is not well-established. Current research has indicated T-helper cell 17–inducing roles but also tolerogenic roles....

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Detalles Bibliográficos
Autores principales: Schmetterer, Klaus G., Neunkirchner, Alina, Wojta-Stremayr, Daniela, Leitner, Judith, Steinberger, Peter, Pickl, Winfried F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422363/
https://www.ncbi.nlm.nih.gov/pubmed/25398767
http://dx.doi.org/10.1096/fj.14-257584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422363/
https://www.ncbi.nlm.nih.gov/pubmed/25398767
http://dx.doi.org/10.1096/fj.14-257584

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