Damaging the Integrated HIV Proviral DNA with TALENs

HIV-1 integrates its proviral DNA genome into the host genome, presenting barriers for virus eradication. Several new gene-editing technologies have emerged that could potentially be used to damage integrated proviral DNA. In this study, we use transcription activator-like effector nucleases (TALENs...

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Detalles Bibliográficos
Autores principales: Strong, Christy L., Guerra, Horacio P., Mathew, Kiran R., Roy, Nervik, Simpson, Lacy R., Schiller, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422436/
https://www.ncbi.nlm.nih.gov/pubmed/25946221
http://dx.doi.org/10.1371/journal.pone.0125652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422436/
https://www.ncbi.nlm.nih.gov/pubmed/25946221
http://dx.doi.org/10.1371/journal.pone.0125652

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