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Skeletal muscle insulin resistance in salt-sensitive hypertension: role of angiotensin II activation of NFκB

BACKGROUND: We have previously shown that in hypertensive Dahl salt-sensitive (DS) rats, impaired endothelium-dependent relaxation to acetylcholine and to insulin is mechanistically linked to up-regulation of angiotensin (Ang) II actions and the production of reactive oxygen species (ROS) and to act...

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Detalles Bibliográficos
Autores principales: Zhou, Ming-Sheng, Liu, Chang, Tian, Runxia, Nishiyama, Akira, Raij, Leopoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422462/
https://www.ncbi.nlm.nih.gov/pubmed/25928697
http://dx.doi.org/10.1186/s12933-015-0211-6