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BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma

BACKGROUND: Malignant mesothelioma (MM) arises from mesothelial cells that line the pleural, peritoneal and pericardial surfaces. The majority of MMs are pleural and have been associated with asbestos exposure. Previously, pleural MMs have been genetically characterized by the loss of BAP1 (40-60%)...

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Detalles Bibliográficos
Autores principales: Alakus, Hakan, Yost, Shawn E, Woo, Brian, French, Randall, Lin, Grace Y, Jepsen, Kristen, Frazer, Kelly A, Lowy, Andrew M, Harismendy, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422481/
https://www.ncbi.nlm.nih.gov/pubmed/25889843
http://dx.doi.org/10.1186/s12967-015-0485-1