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BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma
BACKGROUND: Malignant mesothelioma (MM) arises from mesothelial cells that line the pleural, peritoneal and pericardial surfaces. The majority of MMs are pleural and have been associated with asbestos exposure. Previously, pleural MMs have been genetically characterized by the loss of BAP1 (40-60%)...
Autores principales: | Alakus, Hakan, Yost, Shawn E, Woo, Brian, French, Randall, Lin, Grace Y, Jepsen, Kristen, Frazer, Kelly A, Lowy, Andrew M, Harismendy, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422481/ https://www.ncbi.nlm.nih.gov/pubmed/25889843 http://dx.doi.org/10.1186/s12967-015-0485-1 |
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