Molecular Structure-Affinity Relationship of Bufadienolides and Human Serum Albumin In Vitro and Molecular Docking Analysis

The development of bufadienolides as anti-tumor agents is limited due to poor pharmacokinetic properties regarding drug half-lives and toxicity in vivo. These serious factors might be improved by increasing the drug/albumin-binding ratio. This study therefore investigated the relationship between th...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Lu, Guodi, Wang, Honglan, Zhang, Junfeng, Duan, Jinao, Ma, Hongyue, Wu, Qinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422520/
https://www.ncbi.nlm.nih.gov/pubmed/25946161
http://dx.doi.org/10.1371/journal.pone.0126669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422520/
https://www.ncbi.nlm.nih.gov/pubmed/25946161
http://dx.doi.org/10.1371/journal.pone.0126669

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