Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over

BACKGROUND: Exome sequencing has become a popular method to evaluate undirected mutagenesis experiments in mice. However, the most suitable mouse strain for the biological model may be relatively distant from the standard mouse reference genome. For pinpointing causative variants, a matching referen...

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Detalles Bibliográficos
Autores principales: Derdak, Sophia, Sabrautzki, Sibylle, de Angelis, Martin Hrabě, Gut, Marta, Gut, Ivo G, Beltran, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422528/
https://www.ncbi.nlm.nih.gov/pubmed/25943197
http://dx.doi.org/10.1186/s12864-015-1548-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422528/
https://www.ncbi.nlm.nih.gov/pubmed/25943197
http://dx.doi.org/10.1186/s12864-015-1548-7

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