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Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over
BACKGROUND: Exome sequencing has become a popular method to evaluate undirected mutagenesis experiments in mice. However, the most suitable mouse strain for the biological model may be relatively distant from the standard mouse reference genome. For pinpointing causative variants, a matching referen...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422528/ https://www.ncbi.nlm.nih.gov/pubmed/25943197 http://dx.doi.org/10.1186/s12864-015-1548-7 |