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Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice

INTRODUCTION: Systemic lupus erythematosus is associated with a persistent circulation of modified autoantigen-containing apoptotic debris that might be capable of breaking tolerance. We aimed to evaluate apoptotic microvesicles obtained from lupus or control mice for the presence of apoptosis-assoc...

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Detalles Bibliográficos
Autores principales: Dieker, Jürgen, Hilbrands, Luuk, Thielen, Astrid, Dijkman, Henry, Berden, Jo H, van der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422546/
https://www.ncbi.nlm.nih.gov/pubmed/25886192
http://dx.doi.org/10.1186/s13075-015-0617-2