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SDhaP: haplotype assembly for diploids and polyploids via semi-definite programming

BACKGROUND: The goal of haplotype assembly is to infer haplotypes of an individual from a mixture of sequenced chromosome fragments. Limited lengths of paired-end sequencing reads and inserts render haplotype assembly computationally challenging; in fact, most of the problem formulations are known t...

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Detalles Bibliográficos
Autores principales: Das, Shreepriya, Vikalo, Haris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422552/
https://www.ncbi.nlm.nih.gov/pubmed/25885901
http://dx.doi.org/10.1186/s12864-015-1408-5