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Key determinants of target DNA recognition by retroviral intasomes

BACKGROUND: Retroviral integration favors weakly conserved palindrome sequences at the sites of viral DNA joining and generates a short (4–6 bp) duplication of host DNA flanking the provirus. We previously determined two key parameters that underlie the target DNA preference for prototype foamy viru...

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Detalles Bibliográficos
Autores principales: Serrao, Erik, Ballandras-Colas, Allison, Cherepanov, Peter, Maertens, Goedele N, Engelman, Alan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422553/
https://www.ncbi.nlm.nih.gov/pubmed/25924943
http://dx.doi.org/10.1186/s12977-015-0167-3