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Key determinants of target DNA recognition by retroviral intasomes
BACKGROUND: Retroviral integration favors weakly conserved palindrome sequences at the sites of viral DNA joining and generates a short (4–6 bp) duplication of host DNA flanking the provirus. We previously determined two key parameters that underlie the target DNA preference for prototype foamy viru...
Autores principales: | Serrao, Erik, Ballandras-Colas, Allison, Cherepanov, Peter, Maertens, Goedele N, Engelman, Alan N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422553/ https://www.ncbi.nlm.nih.gov/pubmed/25924943 http://dx.doi.org/10.1186/s12977-015-0167-3 |
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