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Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome

Cells react to nutritional cues in changing environments via the integrated action of signaling, transcriptional, and metabolic networks. Mechanistic insight into signaling processes is often complicated because ubiquitous feedback loops obscure causal relationships. Consequently, the endogenous inp...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana Paula, Dimopoulos, Sotiris, Busetto, Alberto Giovanni, Christen, Stefan, Dechant, Reinhard, Falter, Laura, Haghir Chehreghani, Morteza, Jozefczuk, Szymon, Ludwig, Christina, Rudroff, Florian, Schulz, Juliane Caroline, González, Asier, Soulard, Alexandre, Stracka, Daniele, Aebersold, Ruedi, Buhmann, Joachim M, Hall, Michael N, Peter, Matthias, Sauer, Uwe, Stelling, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422559/
https://www.ncbi.nlm.nih.gov/pubmed/25888284
http://dx.doi.org/10.15252/msb.20145475