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Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome
Cells react to nutritional cues in changing environments via the integrated action of signaling, transcriptional, and metabolic networks. Mechanistic insight into signaling processes is often complicated because ubiquitous feedback loops obscure causal relationships. Consequently, the endogenous inp...
Autores principales: | Oliveira, Ana Paula, Dimopoulos, Sotiris, Busetto, Alberto Giovanni, Christen, Stefan, Dechant, Reinhard, Falter, Laura, Haghir Chehreghani, Morteza, Jozefczuk, Szymon, Ludwig, Christina, Rudroff, Florian, Schulz, Juliane Caroline, González, Asier, Soulard, Alexandre, Stracka, Daniele, Aebersold, Ruedi, Buhmann, Joachim M, Hall, Michael N, Peter, Matthias, Sauer, Uwe, Stelling, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422559/ https://www.ncbi.nlm.nih.gov/pubmed/25888284 http://dx.doi.org/10.15252/msb.20145475 |
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