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Induced Pluripotent Stem Cell Derived Macrophages as a Cellular System to Study Salmonella and Other Pathogens

A number of pathogens, including several human-restricted organisms, persist and replicate within macrophages (Mφs) as a key step in pathogenesis. The mechanisms underpinning such host-restricted intracellular adaptations are poorly understood, in part, due to a lack of appropriate model systems. He...

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Detalles Bibliográficos
Autores principales: Hale, Christine, Yeung, Amy, Goulding, David, Pickard, Derek, Alasoo, Kaur, Powrie, Fiona, Dougan, Gordon, Mukhopadhyay, Subhankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422593/
https://www.ncbi.nlm.nih.gov/pubmed/25946027
http://dx.doi.org/10.1371/journal.pone.0124307