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Induced Pluripotent Stem Cell Derived Macrophages as a Cellular System to Study Salmonella and Other Pathogens
A number of pathogens, including several human-restricted organisms, persist and replicate within macrophages (Mφs) as a key step in pathogenesis. The mechanisms underpinning such host-restricted intracellular adaptations are poorly understood, in part, due to a lack of appropriate model systems. He...
Autores principales: | Hale, Christine, Yeung, Amy, Goulding, David, Pickard, Derek, Alasoo, Kaur, Powrie, Fiona, Dougan, Gordon, Mukhopadhyay, Subhankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422593/ https://www.ncbi.nlm.nih.gov/pubmed/25946027 http://dx.doi.org/10.1371/journal.pone.0124307 |
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