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An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei

Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library in T. brucei bloodstream forms, we identified a member of the mitochondrial carrier family, TbMCP14,...

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Detalles Bibliográficos
Autores principales: de Macêdo, Juan P., Schumann Burkard, Gabriela, Niemann, Moritz, Barrett, Michael P., Vial, Henri, Mäser, Pascal, Roditi, Isabel, Schneider, André, Bütikofer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422618/
https://www.ncbi.nlm.nih.gov/pubmed/25946070
http://dx.doi.org/10.1371/journal.ppat.1004875