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An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei
Elucidating the mechanism of action of trypanocidal compounds is an important step in the development of more efficient drugs against Trypanosoma brucei. In a screening approach using an RNAi library in T. brucei bloodstream forms, we identified a member of the mitochondrial carrier family, TbMCP14,...
Autores principales: | de Macêdo, Juan P., Schumann Burkard, Gabriela, Niemann, Moritz, Barrett, Michael P., Vial, Henri, Mäser, Pascal, Roditi, Isabel, Schneider, André, Bütikofer, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422618/ https://www.ncbi.nlm.nih.gov/pubmed/25946070 http://dx.doi.org/10.1371/journal.ppat.1004875 |
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