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Reduced CSF Water Influx in Alzheimer’s Disease Supporting the β-Amyloid Clearance Hypothesis

OBJECTIVE: To investigate whether water influx into cerebrospinal fluid (CSF) space is reduced in Alzheimer’s patients as previously shown in the transgenic mouse model for Alzheimer’s disease. METHODS: Ten normal young volunteers (young control, 21-30 years old), ten normal senior volunteers (senio...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuji, Nakamura, Yukihiro, Yamada, Kenichi, Igarashi, Hironaka, Kasuga, Kensaku, Yokoyama, Yuichi, Ikeuchi, Takeshi, Nishizawa, Masatoyo, Kwee, Ingrid L., Nakada, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422624/
https://www.ncbi.nlm.nih.gov/pubmed/25946191
http://dx.doi.org/10.1371/journal.pone.0123708