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Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Galβ1-3/4GlcNAc

Galectins represent β-galactoside-binding proteins and are known to bind Galβ1-3/4GlcNAc disaccharides (abbreviated as LN1 and LN2, respectively). Despite high sequence and structural homology shared by the carbohydrate recognition domain (CRD) of all galectin members, how each galectin displays dif...

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Detalles Bibliográficos
Autores principales: Hsieh, Tung-Ju, Lin, Hsien-Ya, Tu, Zhijay, Huang, Bo-Shun, Wu, Shang-Chuen, Lin, Chun-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422656/
https://www.ncbi.nlm.nih.gov/pubmed/25945972
http://dx.doi.org/10.1371/journal.pone.0125946