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Single Cell Quantification of Reporter Gene Expression in Live Adult Caenorhabditis elegans Reveals Reproducible Cell-Specific Expression Patterns and Underlying Biological Variation

In multicellular organisms such as Caenorhabditis elegans, differences in complex phenotypes such as lifespan correlate with the level of expression of particular engineered reporter genes. In single celled organisms, quantitative understanding of responses to extracellular signals and of cell-to-ce...

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Detalles Bibliográficos
Autores principales: Mendenhall, Alexander R., Tedesco, Patricia M., Sands, Bryan, Johnson, Thomas E., Brent, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422670/
https://www.ncbi.nlm.nih.gov/pubmed/25946008
http://dx.doi.org/10.1371/journal.pone.0124289