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Single Cell Quantification of Reporter Gene Expression in Live Adult Caenorhabditis elegans Reveals Reproducible Cell-Specific Expression Patterns and Underlying Biological Variation
In multicellular organisms such as Caenorhabditis elegans, differences in complex phenotypes such as lifespan correlate with the level of expression of particular engineered reporter genes. In single celled organisms, quantitative understanding of responses to extracellular signals and of cell-to-ce...
Autores principales: | Mendenhall, Alexander R., Tedesco, Patricia M., Sands, Bryan, Johnson, Thomas E., Brent, Roger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422670/ https://www.ncbi.nlm.nih.gov/pubmed/25946008 http://dx.doi.org/10.1371/journal.pone.0124289 |
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