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Long-Term Safety of Repeated Blood-Brain Barrier Opening via Focused Ultrasound with Microbubbles in Non-Human Primates Performing a Cognitive Task

Focused Ultrasound (FUS) coupled with intravenous administration of microbubbles (MB) is a non-invasive technique that has been shown to reliably open (increase the permeability of) the blood-brain barrier (BBB) in multiple in vivo models including non-human primates (NHP). This procedure has shown...

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Detalles Bibliográficos
Autores principales: Downs, Matthew E., Buch, Amanda, Sierra, Carlos, Karakatsani, Maria Eleni, Chen, Shangshang, Konofagou, Elisa E., Ferrera, Vincent P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422704/
https://www.ncbi.nlm.nih.gov/pubmed/25945493
http://dx.doi.org/10.1371/journal.pone.0125911