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Long-Term Safety of Repeated Blood-Brain Barrier Opening via Focused Ultrasound with Microbubbles in Non-Human Primates Performing a Cognitive Task
Focused Ultrasound (FUS) coupled with intravenous administration of microbubbles (MB) is a non-invasive technique that has been shown to reliably open (increase the permeability of) the blood-brain barrier (BBB) in multiple in vivo models including non-human primates (NHP). This procedure has shown...
Autores principales: | Downs, Matthew E., Buch, Amanda, Sierra, Carlos, Karakatsani, Maria Eleni, Chen, Shangshang, Konofagou, Elisa E., Ferrera, Vincent P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422704/ https://www.ncbi.nlm.nih.gov/pubmed/25945493 http://dx.doi.org/10.1371/journal.pone.0125911 |
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