Neurotensin—regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis

OBJECTIVE: Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR-133α expression in colonic epithelial cells. We investigated the role of miR-133α in NT-associated colonic inflammation in vitro and in vivo. DESIGN: miR-133α and aftiphili...

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Detalles Bibliográficos
Autores principales: Law, Ivy Ka Man, Bakirtzi, Kyriaki, Polytarchou, Christos, Oikonomopoulos, Angelos, Hommes, Daniel, Iliopoulos, Dimitrios, Pothoulakis, Charalabos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422787/
https://www.ncbi.nlm.nih.gov/pubmed/25112884
http://dx.doi.org/10.1136/gutjnl-2014-307329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422787/
https://www.ncbi.nlm.nih.gov/pubmed/25112884
http://dx.doi.org/10.1136/gutjnl-2014-307329

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