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Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration

As part of an investigative nephrotoxicity study, kidney tissues from juvenile rats orally administered dabrafenib at different age intervals between postnatal day (PND) 7 to 35 were investigated by MALDI and LDI imaging mass spectrometry (IMS) to determine the chemical composition of tubular deposi...

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Detalles Bibliográficos
Autores principales: Groseclose, M. Reid, Laffan, Susan B., Frazier, Kendall S., Hughes-Earle, Angela, Castellino, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422858/
https://www.ncbi.nlm.nih.gov/pubmed/25804893
http://dx.doi.org/10.1007/s13361-015-1103-4