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Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration
As part of an investigative nephrotoxicity study, kidney tissues from juvenile rats orally administered dabrafenib at different age intervals between postnatal day (PND) 7 to 35 were investigated by MALDI and LDI imaging mass spectrometry (IMS) to determine the chemical composition of tubular deposi...
Autores principales: | Groseclose, M. Reid, Laffan, Susan B., Frazier, Kendall S., Hughes-Earle, Angela, Castellino, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422858/ https://www.ncbi.nlm.nih.gov/pubmed/25804893 http://dx.doi.org/10.1007/s13361-015-1103-4 |
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