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Large-Scale Mass Spectrometry Imaging Investigation of Consequences of Cortical Spreading Depression in a Transgenic Mouse Model of Migraine

Cortical spreading depression (CSD) is the electrophysiological correlate of migraine aura. Transgenic mice carrying the R192Q missense mutation in the Cacna1a gene, which in patients causes familial hemiplegic migraine type 1 (FHM1), exhibit increased propensity to CSD. Herein, mass spectrometry im...

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Detalles Bibliográficos
Autores principales: Carreira, Ricardo J., Shyti, Reinald, Balluff, Benjamin, Abdelmoula, Walid M., van Heiningen, Sandra H., van Zeijl, Rene J., Dijkstra, Jouke, Ferrari, Michel D., Tolner, Else A., McDonnell, Liam A., van den Maagdenberg, Arn M. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422864/
https://www.ncbi.nlm.nih.gov/pubmed/25877011
http://dx.doi.org/10.1007/s13361-015-1136-8