MITOsym®: A Mechanistic, Mathematical Model of Hepatocellular Respiration and Bioenergetics

PURPOSE: MITOsym, a new mathematical model of hepatocellular respiration and bioenergetics, has been developed in partnership with the DILIsym® model with the purpose of translating in vitro compound screening data into predictions of drug induced liver injury (DILI) risk for patients. The combined...

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Detalles Bibliográficos
Autores principales: Yang, Y., Nadanaciva, S., Will, Y., Woodhead, J. L., Howell, B. A., Watkins, P. B., Siler, S. Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422870/
https://www.ncbi.nlm.nih.gov/pubmed/25504454
http://dx.doi.org/10.1007/s11095-014-1591-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422870/
https://www.ncbi.nlm.nih.gov/pubmed/25504454
http://dx.doi.org/10.1007/s11095-014-1591-0

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