Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy

INTRODUCTION: Podocalyxin (gene name PODXL) is a CD34-related sialomucin implicated in the regulation of cell adhesion, migration and polarity. Upregulated expression of podocalyxin is linked to poor patient survival in epithelial cancers. However, it is not known if podocalyxin has a functional rol...

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Detalles Bibliográficos
Autores principales: Snyder, Kimberly A, Hughes, Michael R, Hedberg, Bradley, Brandon, Jill, Hernaez, Diana Canals, Bergqvist, Peter, Cruz, Frederic, Po, Kelvin, Graves, Marcia L, Turvey, Michelle E, Nielsen, Julie S, Wilkins, John A, McColl, Shaun R, Babcook, John S, Roskelley, Calvin D, McNagny, Kelly M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423095/
https://www.ncbi.nlm.nih.gov/pubmed/25887862
http://dx.doi.org/10.1186/s13058-015-0562-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423095/
https://www.ncbi.nlm.nih.gov/pubmed/25887862
http://dx.doi.org/10.1186/s13058-015-0562-7

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