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miR-221 facilitates the TGFbeta1-induced epithelial-mesenchymal transition in human bladder cancer cells by targeting STMN1

BACKGROUND: Distant metastasis is the major cause of cancer-related death, and epithelial-to-mesenchymal transition (EMT) has a critical role in this process. Accumulating evidence indicates that EMT can be regulated by microRNAs (miRNAs). miR-221, as oncogenes in several human cancers, was signific...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Cao, Jian, Zhao, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423111/
https://www.ncbi.nlm.nih.gov/pubmed/25928257
http://dx.doi.org/10.1186/s12894-015-0028-3