PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness

BACKGROUND: The local invasion of tumor cells into the surrounding tissue is the first and most critical step of the metastatic cascade. Cells can invade either collectively, or individually. Individual cancer cell invasion can occur in the mesenchymal or amoeboid mode, which are mutually interchang...

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Detalles Bibliográficos
Autores principales: Vaškovičová, Katarína, Szabadosová, Emilia, Čermák, Vladimír, Gandalovičová, Aneta, Kasalová, Lenka, Rösel, Daniel, Brábek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423130/
https://www.ncbi.nlm.nih.gov/pubmed/25924946
http://dx.doi.org/10.1186/s12885-015-1347-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423130/
https://www.ncbi.nlm.nih.gov/pubmed/25924946
http://dx.doi.org/10.1186/s12885-015-1347-1

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