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PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness
BACKGROUND: The local invasion of tumor cells into the surrounding tissue is the first and most critical step of the metastatic cascade. Cells can invade either collectively, or individually. Individual cancer cell invasion can occur in the mesenchymal or amoeboid mode, which are mutually interchang...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423130/ https://www.ncbi.nlm.nih.gov/pubmed/25924946 http://dx.doi.org/10.1186/s12885-015-1347-1 |