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A balancing act: heterochromatin protein 1a and the Polycomb group coordinate their levels to silence chromatin in Drosophila

BACKGROUND: The small non-histone protein Heterochromatin protein 1a (HP1a) plays a vital role in packaging chromatin, most notably in forming constitutive heterochromatin at the centromeres and telomeres. A second major chromatin regulating system is that of the Polycomb/trithorax groups of genes w...

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Detalles Bibliográficos
Autores principales: Cabrera, Janel R, Olcese, Ursula, Horabin, Jamila I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423169/
https://www.ncbi.nlm.nih.gov/pubmed/25954320
http://dx.doi.org/10.1186/s13072-015-0010-z