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CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease

Mitochondrial dysfunction, often characterized by massive fission and other morphological abnormalities, is a well-known risk factor for Alzheimer's disease (AD). One causative mechanism underlying AD-associated mitochondrial dysfunction is thought to be amyloid-β (Aβ), yet the pathways between...

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Detalles Bibliográficos
Autores principales: Byun, J, Son, S M, Cha, M-Y, Shong, M, Hwang, Y J, Kim, Y, Ryu, H, Moon, M, Kim, K-S, Mook-Jung, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423180/
https://www.ncbi.nlm.nih.gov/pubmed/25361083
http://dx.doi.org/10.1038/cdd.2014.184