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Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons

OBJECTIVE: Endocannabinoids and neuropeptide Y (NPY) promote energy storage via central and peripheral mechanisms. In the hypothalamus, the two systems were suggested to interact. To investigate such interplay also in non-hypothalamic tissues, we evaluated endocannabinoid levels in obese OE-NPY(DβH)...

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Detalles Bibliográficos
Autores principales: Vähätalo, L H, Ruohonen, S T, Mäkelä, S, Ailanen, L, Penttinen, A-M, Stormi, T, Kauko, T, Piscitelli, F, Silvestri, C, Savontaus, E, Di Marzo, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423197/
https://www.ncbi.nlm.nih.gov/pubmed/25915740
http://dx.doi.org/10.1038/nutd.2015.1