Role of RNase H1 in DNA repair: removal of single ribonucleotide misincorporated into DNA in collaboration with RNase H2

Several RNases H1 cleave the RNA-DNA junction of Okazaki fragment-like RNA-DNA/DNA substrate. This activity, termed 3’-junction ribonuclease (3’-JRNase) activity, is different from the 5’-JRNase activity of RNase H2 that cleaves the 5’-side of the ribonucleotide of the RNA-DNA junction and is requir...

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Detalles Bibliográficos
Autores principales: Tannous, Elias, Kanaya, Eiko, Kanaya, Shigenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423430/
https://www.ncbi.nlm.nih.gov/pubmed/25951507
http://dx.doi.org/10.1038/srep09969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423430/
https://www.ncbi.nlm.nih.gov/pubmed/25951507
http://dx.doi.org/10.1038/srep09969

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