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Wnt blockers inhibit the proliferation of lung cancer stem cells

BACKGROUND: Previous study has confirmed that the occurrence of Wnt pathway activation is associated with risk of non-small-cell lung cancer recurrence. However, whether the pharmacologic blocking of the Wnt signaling pathway could provide therapeutic possibility remains unknown. The aim of the pres...

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Detalles Bibliográficos
Autores principales: Zhang, Xueyan, Lou, Yuqing, Zheng, Xiaoxuan, Wang, Huimin, Sun, Jiayuan, Dong, Qianggang, Han, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423515/
https://www.ncbi.nlm.nih.gov/pubmed/25960639
http://dx.doi.org/10.2147/DDDT.S76602