Glycopeptide Analogues of PSGL-1 Inhibit P-Selectin In Vitro and In Vivo

Blockade of P-selectin/PSGL-1 interactions holds significant potential for treatment of disorders of innate immunity, thrombosis, and cancer. Current inhibitors remain limited due to low binding affinity or by the recognized disadvantages inherent to chronic administration of antibody therapeutics....

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Venkata R, Sardar, Mohammed Y. R., Yu, Ying, Song, Xuezheng, Haller, Carolyn, Dai, Erbin, Wang, Xiacong, Hanjaya-Putra, Donny, Sun, Lijun, Morikis, Vasilios, Simon, Scott I., Woods, Robert, Cummings, Richard D., Chaikof, Elliot L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423566/
https://www.ncbi.nlm.nih.gov/pubmed/25824568
http://dx.doi.org/10.1038/ncomms7387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423566/
https://www.ncbi.nlm.nih.gov/pubmed/25824568
http://dx.doi.org/10.1038/ncomms7387

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