Cargando…
Glycopeptide Analogues of PSGL-1 Inhibit P-Selectin In Vitro and In Vivo
Blockade of P-selectin/PSGL-1 interactions holds significant potential for treatment of disorders of innate immunity, thrombosis, and cancer. Current inhibitors remain limited due to low binding affinity or by the recognized disadvantages inherent to chronic administration of antibody therapeutics....
Autores principales: | Krishnamurthy, Venkata R, Sardar, Mohammed Y. R., Yu, Ying, Song, Xuezheng, Haller, Carolyn, Dai, Erbin, Wang, Xiacong, Hanjaya-Putra, Donny, Sun, Lijun, Morikis, Vasilios, Simon, Scott I., Woods, Robert, Cummings, Richard D., Chaikof, Elliot L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423566/ https://www.ncbi.nlm.nih.gov/pubmed/25824568 http://dx.doi.org/10.1038/ncomms7387 |
Ejemplares similares
-
Peritoneal macrophages express both P-selectin and PSGL-1
por: Tchernychev, Boris, et al.
Publicado: (2003) -
Dimerization of P-Selectin Glycoprotein Ligand-1 (PSGL-1) Required for Optimal Recognition of P-Selectin
por: Snapp, Karen R., et al.
Publicado: (1998) -
The PSGL-1–L-selectin signaling complex regulates neutrophil adhesion under flow
por: Stadtmann, Anika, et al.
Publicado: (2013) -
The Interaction of Selectins and PSGL-1 as a Key Component in Thrombus Formation and Cancer Progression
por: Kappelmayer, János, et al.
Publicado: (2017) -
P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is a Physiological Ligand for E-Selectin in Mediating T Helper 1 Lymphocyte Migration
por: Hirata, Takako, et al.
Publicado: (2000)