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An integrative framework for the identification of double minute chromosomes using next generation sequencing data

BACKGROUND: Double minute chromosomes are circular fragments of DNA whose presence is associated with the onset of certain cancers. Double minutes are lethal, as they are highly amplified and typically contain oncogenes. Locating double minutes can supplement the process of cancer diagnosis, and it...

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Detalles Bibliográficos
Autores principales: Hayes, Matthew, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423570/
https://www.ncbi.nlm.nih.gov/pubmed/25953282
http://dx.doi.org/10.1186/1471-2156-16-S2-S1