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An integrative framework for the identification of double minute chromosomes using next generation sequencing data
BACKGROUND: Double minute chromosomes are circular fragments of DNA whose presence is associated with the onset of certain cancers. Double minutes are lethal, as they are highly amplified and typically contain oncogenes. Locating double minutes can supplement the process of cancer diagnosis, and it...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423570/ https://www.ncbi.nlm.nih.gov/pubmed/25953282 http://dx.doi.org/10.1186/1471-2156-16-S2-S1 |