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Ciprofloxacin Derivatives Affect Parasite Cell Division and Increase the Survival of Mice Infected with Toxoplasma gondii

Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a worldwide disease whose clinical manifestations include encephalitis and congenital malformations in newborns. Previously, we described the synthesis of new ethyl-ester derivatives of the antibiotic ciprofloxacin with ~40-fold increased...

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Detalles Bibliográficos
Autores principales: Martins-Duarte, Erica S., Dubar, Faustine, Lawton, Philippe, França da Silva, Cristiane, C. Soeiro, Maria de Nazaré, de Souza, Wanderley, Biot, Christophe, Vommaro, Rossiane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423777/
https://www.ncbi.nlm.nih.gov/pubmed/25950173
http://dx.doi.org/10.1371/journal.pone.0125705