Identification of Variants in Primary and Recurrent Glioblastoma Using a Cancer-Specific Gene Panel and Whole Exome Sequencing

Glioblastoma (GBM) is an aggressive, malignant brain tumor typically resulting in death of the patient within one year following diagnosis; and those who survive beyond this point usually present with tumor recurrence within two years (5-year survival is 5%). The genetic heterogeneity of GBM has mad...

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Detalles Bibliográficos
Autores principales: Virk, Selene M., Gibson, Richard M., Quinones-Mateu, Miguel E., Barnholtz-Sloan, Jill S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423782/
https://www.ncbi.nlm.nih.gov/pubmed/25950952
http://dx.doi.org/10.1371/journal.pone.0124178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423782/
https://www.ncbi.nlm.nih.gov/pubmed/25950952
http://dx.doi.org/10.1371/journal.pone.0124178

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