A Two-Component DNA-Prime/Protein-Boost Vaccination Strategy for Eliciting Long-Term, Protective T Cell Immunity against Trypanosoma cruzi

In this study, we evaluated the long-term efficacy of a two-component subunit vaccine against Trypanosoma cruzi infection. C57BL/6 mice were immunized with TcG2/TcG4 vaccine delivered by a DNA-prime/Protein-boost (D/P) approach and challenged with T. cruzi at 120 or 180 days post-vaccination (dpv)....

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Detalles Bibliográficos
Autores principales: Gupta, Shivali, Garg, Nisha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423834/
https://www.ncbi.nlm.nih.gov/pubmed/25951312
http://dx.doi.org/10.1371/journal.ppat.1004828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423834/
https://www.ncbi.nlm.nih.gov/pubmed/25951312
http://dx.doi.org/10.1371/journal.ppat.1004828

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