Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast

Cells respond to their environment by modulating protein levels through mRNA transcription and post-transcriptional control. Modest observed correlations between global steady-state mRNA and protein measurements have been interpreted as evidence that mRNA levels determine roughly 40% of the variatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Csárdi, Gábor, Franks, Alexander, Choi, David S., Airoldi, Edoardo M., Drummond, D. Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423881/
https://www.ncbi.nlm.nih.gov/pubmed/25950722
http://dx.doi.org/10.1371/journal.pgen.1005206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423881/
https://www.ncbi.nlm.nih.gov/pubmed/25950722
http://dx.doi.org/10.1371/journal.pgen.1005206

Ejemplares similares