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Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy

While circadian dysfunction and neurodegeneration are correlated, the mechanism for this is not understood. It is not known if age-dependent circadian dysfunction leads to neurodegeneration or vice-versa, and the proteins that mediate the effect remain unidentified. Here, we show that the knock-down...

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Detalles Bibliográficos
Autores principales: Means, John C., Venkatesan, Anandakrishnan, Gerdes, Bryan, Fan, Jin-Yuan, Bjes, Edward S., Price, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423883/
https://www.ncbi.nlm.nih.gov/pubmed/25951229
http://dx.doi.org/10.1371/journal.pgen.1005171