A Novel Quantitative Hemolytic Assay Coupled with Restriction Fragment Length Polymorphisms Analysis Enabled Early Diagnosis of Atypical Hemolytic Uremic Syndrome and Identified Unique Predisposing Mutations in Japan

For thrombotic microangiopathies (TMAs), the diagnosis of atypical hemolytic uremic syndrome (aHUS) is made by ruling out Shiga toxin-producing Escherichia coli (STEC)-associated HUS and ADAMTS13 activity-deficient thrombotic thrombocytopenic purpura (TTP), often using the exclusion criteria for sec...

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Detalles Bibliográficos
Autores principales: Yoshida, Yoko, Miyata, Toshiyuki, Matsumoto, Masanori, Shirotani-Ikejima, Hiroko, Uchida, Yumiko, Ohyama, Yoshifumi, Kokubo, Tetsuro, Fujimura, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423893/
https://www.ncbi.nlm.nih.gov/pubmed/25951460
http://dx.doi.org/10.1371/journal.pone.0124655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423893/
https://www.ncbi.nlm.nih.gov/pubmed/25951460
http://dx.doi.org/10.1371/journal.pone.0124655

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