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Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner

The contribution of natural killer (NK) cells to the treatment efficacy of dendritic cell (DC)-based cancer vaccines is being increasingly recognized. Much current efforts to optimize this form of immunotherapy are therefore geared towards harnessing the NK cell-stimulatory ability of DCs. In this s...

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Detalles Bibliográficos
Autores principales: Anguille, Sébastien, Van Acker, Heleen H., Van den Bergh, Johan, Willemen, Yannick, Goossens, Herman, Van Tendeloo, Viggo F., Smits, Evelien L., Berneman, Zwi N., Lion, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423923/
https://www.ncbi.nlm.nih.gov/pubmed/25951230
http://dx.doi.org/10.1371/journal.pone.0123340