Cargando…
Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner
The contribution of natural killer (NK) cells to the treatment efficacy of dendritic cell (DC)-based cancer vaccines is being increasingly recognized. Much current efforts to optimize this form of immunotherapy are therefore geared towards harnessing the NK cell-stimulatory ability of DCs. In this s...
Autores principales: | Anguille, Sébastien, Van Acker, Heleen H., Van den Bergh, Johan, Willemen, Yannick, Goossens, Herman, Van Tendeloo, Viggo F., Smits, Evelien L., Berneman, Zwi N., Lion, Eva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423923/ https://www.ncbi.nlm.nih.gov/pubmed/25951230 http://dx.doi.org/10.1371/journal.pone.0123340 |
Ejemplares similares
-
Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity
por: Van den Bergh, Johan, et al.
Publicado: (2015) -
Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells
por: Van Acker, Heleen H., et al.
Publicado: (2016) -
Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells
por: Van Acker, Heleen H., et al.
Publicado: (2017) -
Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion
por: Van Acker, Heleen H., et al.
Publicado: (2018) -
CD56 Homodimerization and Participation in Anti-Tumor Immune Effector Cell Functioning: A Role for Interleukin-15
por: Van Acker, Heleen H., et al.
Publicado: (2019)